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Baseline MSUS/MBDA score association with Baseline CDAI/DAS28/ESR
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CDAI Baseline
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DAS28/ESR Baseline
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PDUS Baseline
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0.53**
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0.58**
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GSUS Baseline
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0.65**
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0.53**
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mUS7 PDUS Baseline
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0.45*
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0.58**
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mUS7 GSUS Baseline
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0.49*
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0.42*
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MBDA Score Baseline
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0.24
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0.47*
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2 Week MSUS/MBDA score association with 2 Week CDAI/DAS28
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CDAI 2 Week
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DAS28/ESR 2 Week
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PDUS 2 Week
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0.45*
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0.49*
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GSUS 2 Week
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0.62**
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0.52**
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mUS7 PDUS 2 Week
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0.43*
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0.49*
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mUS7 GSUS 2 Week
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0.41*
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0.31
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MBDA Score 2 Week
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0.05
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0.19
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12 Week MSUS/MBDA score association with 12 Week CDAI/DAS28
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CDAI 12 Week
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DAS28/ESR 12 Week
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PDUS 12 Week
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0.38
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0.54**
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GSUS 12 Week
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0.52**
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0.53**
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mUS7 PDUS 12 Week
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0.28
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0.43*
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mUS7 GSUS 12 Week
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0.49*
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0.44*
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MBDA Score 12 Week
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−0.19
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0.05
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Baseline MSUS/MBDA score association with 12 Week change in CDAI/DAS28
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CDAI (Δ 0–12 weeks)
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DAS28/ESR (Δ 0–12 weeks)
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PDUS Baseline
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0.55**
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0.45*
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GSUS Baseline
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0.47*
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0.25
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mUS7 PDUS Baseline
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0.62**
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0.55**
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mUS7 GSUS Baseline
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0.47*
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0.33
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MBDA Score Baseline
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0.44*
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0.50*
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2 Week change in MSUS/MBDA score association with 12 Week change in CDAI/DAS28
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CDAI (Δ 0–12 weeks)
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DAS28/ESR (Δ 0–12 weeks)
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PDUS (Δ 0–2 weeks)
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0.37
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0.42*
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GSUS (Δ 0–2 weeks)
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0.44*
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0.42*
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mUS7 PDUS (Δ 0–2 weeks)
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0.47*
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0.57**
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mUS7 GSUS (Δ 0–2 weeks)
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0.56**
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0.51**
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MBDA Score (Δ 0–2 weeks)
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0.22
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0.29
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12 Week change in MSUS/MBDA score association with 12 Week change in CDAI/DAS28
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CDAI (Δ 0–12 week)
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DAS28/ESR (Δ 0–12 week)
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PDUS (Δ 0–12 week)
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0.58**
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0.56**
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GSUS (Δ 0–12 week)
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0.47*
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0.34
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mUS7 PDUS (Δ 0–12 week)
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0.60**
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0.64**
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mUS7 GSUS (Δ 0–12 week)
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0.54**
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0.48*
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MBDA Score (Δ 0–12 week)
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0.44*
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0.59**
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- *p < 0.05, **p < 0.01; PDUS Power doppler ultrasound, GSUS Gray scale ultrasound, mUS7 modified ultrasound 7, MBDA Multi-biomarker Disease activity score, CDAI Clinical disease activity index, DAS28/ESR Disease activity score/erythrocyte sedimentation rate
